Table 2 is a summary of the results of the effects of uvaria chamae on plasma lipid profile in diabetic rats. Xylopiastrum macrocarpum vahl roberty homonyms uvaria chamae p. Two new cbenzylated flavanones from uvaria chamae and c. Uvaria chamae is a climbing shrub or small tree growing up to 4 metres tall. Chamuvaritin 20 is a dihydrobenzylchalcone isolated from uvaria chamae, an african medicinal plant used as purgative and febrifugal 38. This study presents antimicrobial properties of uvaria chamae roots, commonly used for the treatment of various infections in south benin. The results of these investigations could justify traditional used of uvaria chamae in treatment of bacterial dysentery. In vitro antiradical and antisalmonella activities of. Usda, ars, germplasm resources information network. Subchronic toxicity study of ethanolic extract of uvaria. To assess the safety of ethanol extract of uvaria chamae root consumption for the treatment of.
The implication of these results is in defining the role of each plant specimen in traditional recipes for scd management and drug development is presented. Pdf in vitro antisickling activities and phytochemical. Phytochemical composition and biological activities of. Beauv and clerodendron splendens a cheval are known to have various medicinal and therapeutic properties. Uvaria chamae is a climbing shrub or small tree growing up to 4 metres tall328.
Media in category uvaria chamaethe following 2 files are in this category, out of 2 total. Antiausterity agents from uvaria dac and their preferential cytotoxic activity against human pancreatic cancer cell lines in a nutrientdeprived condition. Preliminary investigation of croton californicus var. To study the antivenom properties, albino rats were orally administered with a dose of 400 mg kg 1 body weight and one hour later, the venom was administered intraperitoneally at a dose of 0. Request pdf subchronic toxicity study of ethanolic extract of uvaria chamae root in rats purpose. Standard techniques were employed in crude extraction of roots and. Toxicological studies of herbal antitumor extract uvaria chamae in monosodium glutamate and tamoxifen treated spraguedawley rat tola monday1,4. Ogholo by the esan people of edo state, ayiloko by the igalas, kaskaifi by the. Phytochemical composition and biological activities 555 preparation of plant extracts the leaves of clerodendron splendens and roots of uvarea chamae were airdried at the laboratory bench for 10 days and then ground into a uniform powder using a thomas wiley. Please note that this is a trial program and may end.
Uvaria chamae is a plant used traditionally in treatment of wounds and other ailments. Beauv annonaceae on acute edema of rat paw induced by carrageenan bamba b, golly k j, ouattara a, kone m, doukourou d n, benie c k d, diarrassouba d, kamou r, ouattara k. Download fulltext pdf download fulltext pdf antibacterial activity of chalcone and dihydrochalcone compounds from uvaria chamae roots against multidrugresistant bacteria. Cytotoxic cbenzylated chalcone and other constituents of. Pdf toxicological studies of herbal antitumor extract. Aromatic constituents from uvaria chamae sciencedirect. Chamuvaritin 20 is a dihydrobenzylchalcone isolated from uvaria chamae, an african medicinal plant used as purgative and febrifugal. It is also known as finger root or bush banana and it belong to the climbing large shrub or small native tree in tropical west and central africa. Cytotoxic cbenzylated flavonoids from uvaria chamae the. The common name refers to the fruit growing in its small bunches. All structured data from the file and property namespaces is available under the creative commons cc0 license. Phytochemical screening and effect of ethanolic root. Uvaria macrocarpa vahl uvaria macrocarpa vahl ex dc.
This phytochemical was mutagenic in salmonella typhimurium strains ta98 and ta100 via the activation by the hepatic microsomal enzyme preparation. Uvaria is a genus of flowering plants in the soursop family, annonaceae. Macro elemental composition of uvaria chamae leaves with abstract, chapter 15, references and questionnaire. Haematological and genotoxicity evaluations of phytochemical compounds from nhexane extract of uvaria chamae stem on selected organs in mice oladipupo r. A novel monobenzylated monoterpene, chamanen, has been isolated from the root bark of uvaria chamae. Antidiabetic and hypolipidemic activities of hydroethanolic root. African journal of biotechnology in vitro antisickling. The following corrections should be applied to the article. This study aimed to produce scientific data on in vitro and in vivo efficacy of uvaria chamae, lantana camara and phyllantus amarus on multiresistant salmonella spp isolated in benin.
Pdf comparative assessment of antibacterial activity of. Research article antibacterial activity of chalcone and. Antiinflammatory activity of the aqueous macerate of leaves of uvaria chamae p. Phytochemical composition, antioxidant and antibacterial. Pdf phytochemical composition and biological activities of uvaria. Evaluation of invivo anti salmonella activity of uvaria. In this region of the world, it is identified by numerous names such as. In the article titled antibacterial activity of chalcone and dihydrochalcone compounds from uvaria chamae roots against multidrugresistant bacteria, minor errors were found which happened during the production process. Pdf toxicological studies of herbal antitumor extract uvaria. In tables 2 and 3, the antisickling activities glycosides is an indication that a recipe that contain u. It is a climbing plant commonly found in west africa 9. Beauv and clerodendron splendens a cheval are known to have various medicinal and therapeutic. African journal of microbiology research qualitative.
Program requirement research proposal submitted by. Tumor cases are being linked to diet, lack of physical activity and overweight with monosodium glutamate msg and tamoxifen tam playing some roles. Their antiinflammatory and oxytocic properties were assessed in this study. Title african flowering plants database publication author website. Uvaria chamae is a medicinal plant that belongs to the family, annonaceae. The plasma cholesterol and ldl levels of diabetic rats treated with the extracts were significantly reduced p download fulltext pdf. The generic name uvaria is derived from the latin uva meaning grape, likely because the edible fruit of some species in the genus resemble grapes species are distributed throughout the old world tropics. Journal of essential oil research 1999, 11 1, 2326. Uvaretin, a new antitumor agent from uvaria acuminata. Uvaria chamae in the germplasm resources information network grin, u. Macro elemental composition of uvaria chamae leaves chapter one introduction background of the study varia chamae is a nigerian medicinal plant that belongs to the family of annonaceae.
The in vivo anti malarial activities of uvaria chamae and. Uvaria chamae, commonly known as finger root or bush banana belongs to the family annonaceae. Phytoconstituants of two extracts of uvaria chamae tannins, flavonoids, and phenols were also assayed by colorimetric method. Uvaria chamae annonaceae, phyllantus amarus phyllantaceae and lantana camara verbenaceae are empirically alleged to be used as beninese medicinal plants in the treatment of salmonellosis. Issued as a pdf on the internet, it contains basic information on over 250 species of plants used for food.
As for the roots essential oils from uvaria chamae and uvaria. The in vivo anti malarial activities of uvaria chamae and hippocratea africana article pdf available in pathogens and global health 1007. Uvaria chamae, commonly known as finger root or bush banana is a climbing large shrub or. Two known polyoxygenated cyclohexene derivatives, ferrudiol and zeylenol, and a new.
In vitro antiradical and antisalmonella activities of sarcocephalus latifolius, lannea rteri, uvaria chamae, parkia biglobosa and khaya senegalensis. A novel 1indanone isolated from uvaria afzelii roots,natural product research,23. Antimicrobial susceptibility tests were performed against several multidrugresistant bacteria using the mueller hilton well agar diffusion method. Diabetes mellitus was experimentally induced after the rats were fasted overnight by administering intraperitoneally, 60 mgkg. Three indigenous plants used in anticancer remedies. Macro elemental composition of uvaria chamae leaves. Uvaria chamae, commonly known as finger root or bush banana is a climbing large shrub or small tree native to tropical west and central africa where it grows in wet and dry forests and coastal scrublands. Antibacterial properties of uvaria chamae, congronema.
Example 5 crushing and alcoholic extraction, preferably with ethanol of the plant uvaria chamae as described in example 1 but using the plant uvaria chamae in place of the plant fagara xanthoxyloides, it cannot be obtained from a on the one hand a crude powder for grinding the plant uvar a 35 chamae and, on the other hand an extract in the. Chamuvaritin 20 is a dihydrobenzylchalcone isolated from uvaria chamae, an african medicinal plant used as purgative and. Files are available under licenses specified on their description page. Essential oil of leaf and root bark of uvaria chamae p.
Access is allocated within two business days of purchase and lasts one year. A new cytotoxic acetogenin, chamuvarinin 1, containing a tetrahydropyran ring with an adjacent bistetrahydrofuran ring, which corresponds to a novel carbon skeleton in this series, was isolated from the roots of uvaria chamae, together with the previously reported acetogenins squamocin 2, desacetyluvaricin 3, and neoannonin 4. Antisickling activity, phytochemicals, plumbago zeylanica, sickle cell disease, uvaria chamae. It is commonly called nkarika ikot by akwa ibomites. The potentials of uvaria chamae as an antidiabetic and hypolipidemic drug candidate are thus tested. The extracts and aspirin were found to inhibit carrageenaninduced paw oedema on albino rats and mice with a strong activity in aspirin having 80.
Their constituents were extracted and then fractionated in order to isolate the active ingredients. The potentials of uvaria chamae as an antidiabetic and hypolipidemic drugcandidate are thus tested. Uvaria chamae, also known as finger root or bush banana, could take its name from the greek wordchamaimeaning on the ground. Pdf in the present work phytochemical composition, antioxidant and antibacterial. Elsohly hn, lasswell wl jr, hufford cd 1979 two new cbenzylated flavanones from uvaria chamae and c nmr analysis of flavanone methyl ethers. Soheila abachi department of environmental sciences faculty of agriculture dalhousie university june 16 2014 supervisor. Pages in category uvaria the following 5 pages are in this category, out of 5 total. Freshly collected uvaria chamae leaves were air dried, powdered and extracted in methanol. Antibacterial activity of chalcone and dihydrochalcone. Haematological and genotoxicity evaluations of phytochemical compounds from nhexane extract of uvaria chamae stem on selected organs in mice. This large genus had about 150 species, but recent molecular analyses have revealed that several smaller genera belong.
This work was conducted on qualitative assessment of crude extracts of u. Pdf phytochemical composition, antioxidant and antibacterial. Three indigenous plants used in anticancer remedies, garcinia kola heckel stem bark, uvaria chamae p. Chamuvarinin, an acetogenin bearing a tetrahydropyran ring. Pdf a novel 1indanone isolated from uvaria afzelii roots.
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